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The Fine LINE: Methylation Drawing the Cancer Landscape

LINE-1 (L1) is the most abundant mammalian transposable element that comprises nearly 20% of the genome, and nearly half of the mammalian genome has stemmed from L1-mediated mobilization. Expression and retrotransposition of L1 are suppressed by complex mechanisms, where the key role belongs to DNA...

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Hlavní autoři: Isabelle R. Miousse, Igor Koturbash
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Limited 2015-01-01
Edice:BioMed Research International
On-line přístup:http://dx.doi.org/10.1155/2015/131547
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