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Application of CRISPR/Cas9 Technology to HBV
More than 240 million people around the world are chronically infected with hepatitis B virus (HBV). Nucleos(t)ide analogs and interferon are the only two families of drugs to treat HBV currently. However, none of these anti-virals directly target the stable nuclear covalently closed circular DNA (c...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
MDPI AG
2015-11-01
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Colecção: | International Journal of Molecular Sciences |
Assuntos: | |
Acesso em linha: | http://www.mdpi.com/1422-0067/16/11/25950 |
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