Hyper-Inflammatory Monocyte Activation Following Endotoxin Exposure in Food Allergic Infants

Several recent studies have reported a key role for innate cell hyper-responsiveness in food allergy. This has predominantly been observed in early life, with evidence that innate immune function may return to baseline if food allergy resolves in later childhood. Hallmarks of hyper-responsiveness in...

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Bibliografiska uppgifter
Huvudupphovsmän: Melanie R. Neeland, Boris Novakovic, Thanh D. Dang, Kirsten P. Perrett, Jennifer J. Koplin, Richard Saffery
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2020-09-01
Serie:Frontiers in Immunology
Ämnen:
monocytes
food allergy
trained immunity
inflammatory response
regulatory T (Treg) cell
Länkar:https://www.frontiersin.org/article/10.3389/fimmu.2020.567981/full
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