Hyper-Inflammatory Monocyte Activation Following Endotoxin Exposure in Food Allergic Infants

Several recent studies have reported a key role for innate cell hyper-responsiveness in food allergy. This has predominantly been observed in early life, with evidence that innate immune function may return to baseline if food allergy resolves in later childhood. Hallmarks of hyper-responsiveness in...

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Bibliographische Detailangaben
Hauptverfasser: Melanie R. Neeland, Boris Novakovic, Thanh D. Dang, Kirsten P. Perrett, Jennifer J. Koplin, Richard Saffery
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020-09-01
Schriftenreihe:Frontiers in Immunology
Schlagworte:
monocytes
food allergy
trained immunity
inflammatory response
regulatory T (Treg) cell
Online Zugang:https://www.frontiersin.org/article/10.3389/fimmu.2020.567981/full
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