In vivo screening reveals interactions between Drosophila Manf and genes involved in the mitochondria and the ubiquinone synthesis pathway

Abstract Background Mesencephalic Astrocyte-derived Neurotrophic Factor (MANF) and Cerebral Dopamine Neurotrophic Factor (CDNF) form an evolutionarily conserved family of neurotrophic factors. Orthologues for MANF/CDNF are the only neurotrophic factors as yet identified in invertebrates with conserv...

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Main Authors: Riitta Lindström, Päivi Lindholm, Mari Palgi, Mart Saarma, Tapio I. Heino
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2017-06-01
Serier:BMC Genetics
Fag:
MANF
CDNF
Genetic screen
Mitochondria
Ubiquinone
Online adgang:http://link.springer.com/article/10.1186/s12863-017-0509-3
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