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EGFR and KRAS mutation coexistence in lung adenocarcinomas

Lung cancer is one of the most common causes of cancer deaths. The development of EGFR targeted therapies, including monoclonal antibodies and tyrosine kinase inhibitors have generated an interest in the molecular characterization of these tumours. KRAS mutations are associated with resistance to EG...

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Autores principales: Vitor Manuel Leitão de Sousa, Maria Reis Silva, Ana Maria Alarcão, Maria João d’Aguiar, Teresa Ferreira, Lina Carvalho
Formato: Artigo
Lenguaje:Inglês
Publicado: DiagnomX 2015-04-01
Colección:Diagnostic Pathology
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Acceso en línea:http://www.diagnosticpathology.eu/content/index.php/dpath/article/view/13
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