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Gene expression within the periaqueductal gray is linked to vocal behavior and early-onset parkinsonism in Pink1 knockout rats

Abstract Background Parkinson’s disease (PD) is a degenerative disease with early-stage pathology hypothesized to manifest in brainstem regions. Vocal deficits, including soft, monotone speech, result in significant clinical and quality of life issues and are present in 90% of PD patients; yet the u...

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Detalhes bibliográficos
Main Authors: Cynthia A. Kelm-Nelson, Stephen Gammie
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2020-09-01
Colecção:BMC Genomics
Assuntos:
Rat
Acesso em linha:http://link.springer.com/article/10.1186/s12864-020-07037-4
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