Lactoferrin impact on gut microbiota in preterm infants with late-onset sepsis or necrotising enterocolitis: the MAGPIE mechanisms of action study

Background: Preterm infants have high rates of morbidity, especially from late-onset sepsis and necrotising enterocolitis. Lactoferrin is an anti-infective milk protein that may act through effects on gut bacteria, metabolites and epithelial cell function. The impact of supplemental lactoferrin in r...

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Bibliografische gegevens
Hoofdauteurs: Nicholas Embleton, Janet Berrington, Stephen Cummings, Jon Dorling, Andrew Ewer, Alessandra Frau, Edmund Juszczak, John Kirby, Christopher Lamb, Clare Lanyon, Lauren Lett, William McGuire, Christopher Probert, Stephen Rushton, Mark Shirley, Christopher Stewart, Gregory R Young
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: NIHR Journals Library 2021-09-01
Reeks:Efficacy and Mechanism Evaluation
Onderwerpen:
humans
infant
infant, newborn
enterocolitis, necrotizing
ltf protein, human
lactoferrin
gastrointestinal microbiome
dysbiosis
enteral nutrition
risk factors
milk
metabolome
high-throughput nucleotide sequencing
infant, premature
sepsis
feces
fatty acids, volatile
immune system
mass spectrometry
clinical protocols
Online toegang:https://doi.org/10.3310/eme08140
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