Defining Surrogate Endpoints for Clinical Trials in Severe Falciparum Malaria.

<h4>Background</h4>Clinical trials in severe falciparum malaria require a large sample size to detect clinically meaningful differences in mortality. This means few interventions can be evaluated at any time. Using a validated surrogate endpoint for mortality would provide a useful alternative allow...

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Główni autorzy:	Atthanee Jeeyapant, Hugh W Kingston, Katherine Plewes, Richard J Maude, Josh Hanson, M Trent Herdman, Stije J Leopold, Thatsanun Ngernseng, Prakaykaew Charunwatthana, Nguyen Hoan Phu, Aniruddha Ghose, M Mahtab Uddin Hasan, Caterina I Fanello, Md Abul Faiz, Tran Tinh Hien, Nicholas P J Day, Nicholas J White, Arjen M Dondorp
Format:	Artigo
Język:	Inglês
Wydane:	Public Library of Science (PLoS) 2017-01-01
Seria:	PLoS ONE
Dostęp online:	https://doi.org/10.1371/journal.pone.0169307
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