PERK-eIF2α activation by avian reticuloendotheliosis virus: a dual strategy to suppress apoptosis and aggravate immunosuppression for enhanced replication

Viral infection induces endoplasmic reticulum stress (ERS) and the subsequent unfolded protein response (UPR), which play a pivotal role in viral replication and pathogenesis. However, the specific implications of ERS in REV infection remain poorly defined. In this study, we demonstrate that reticul...

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Autori principali:	Yitong Wang, Yike Xing, Ziqiang Cheng, Wanqing Xu, Chengui Li, Guihua Wang
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2026-02-01
Serie:	Poultry Science
Soggetti:	REV endoplasmic reticulum stress UPR pathway PERK-eIF2α signaling axis virus replication
Accesso online:	http://www.sciencedirect.com/science/article/pii/S0032579125015342
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