The expansion of MDSCs induced by exosomal PD-L1 promotes the progression of gastric cancer

Abstract Background Myeloid-derived suppressor cells (MDSCs) are the major factor in gastric cancer (GC) immune evasion. Nevertheless, the molecular process underlying the expansion of MDSCs induced by tumor-derived exosomes (TDEs) remains elusive. Methods The levels of exosomal and soluble PD-L1 in...

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Detalhes bibliográficos

Principais autores:	Huaizhi Li, Xu Chen, Shanshan Zheng, Bo Han, Xiang Zhang, Xiaoxia Zheng, Yujia Lu, Qingmin Sun, Xufeng Hu, Jian Wu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2024-09-01
coleção:	Journal of Translational Medicine
Assuntos:	PD-L1 Exosomes MDSCs Gastric cancer
Acesso em linha:	https://doi.org/10.1186/s12967-024-05611-y
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