Immune checkpoint inhibitors break whose heart? Perspectives from cardio-immuno-oncology
Immune checkpoint inhibitors (ICIs) are monoclonal antibody antagonists, which can block cytotoxic T lymphocyte antigen-4 (CTLA-4), programmed death-1/ligand-1 (PD-1/PD-L1) pathways, and other molecules exploited by tumor cells to evade T cell-mediated immune response. ICIs have transformed the trea...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
KeAi Communications Co., Ltd.
2024-03-01
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| シリーズ: | Genes and Diseases |
| 主題: | |
| オンライン・アクセス: | http://www.sciencedirect.com/science/article/pii/S2352304223000478 |
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