Profiling the 3D interaction between germ cell tumors and microenvironmental cells at the transcriptome and secretome level

The tumor microenvironment (TM), consisting of the extracellular matrix (ECM), fibroblasts, endothelial cells, and immune cells, might affect tumor invasiveness and the outcome of standard chemotherapy. This study investigated the cross talk between germ cell tumors (GCT) and surrounding TM cells (m...

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Detalhes bibliográficos

Principais autores:	Margaretha A. Skowron, Katharina Eul, Alexa Stephan, Gillian F. Ludwig, Gamal A. Wakileh, Arthur Bister, Christian Söhngen, Katharina Raba, Patrick Petzsch, Gereon Poschmann, Edmund Osei Kuffour, Daniel Degrandi, Shafaqat Ali, Constanze Wiek, Helmut Hanenberg, Carsten Münk, Kai Stühler, Karl Köhrer, Elvira Mass, Daniel Nettersheim
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2022-09-01
coleção:	Molecular Oncology
Assuntos:	cisplatin resistance extracellular matrix germ cell tumors tumor microenvironment
Acesso em linha:	https://doi.org/10.1002/1878-0261.13282
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