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Shed GP of Ebola virus triggers immune activation and increased vascular permeability.

During Ebola virus (EBOV) infection a significant amount of surface glycoprotein GP is shed from infected cells in a soluble form due to cleavage by cellular metalloprotease TACE. Shed GP and non-structural secreted glycoprotein sGP, both expressed from the same GP gene, have been detected in the bl...

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Principais autores: Beatriz Escudero-Pérez, Valentina A Volchkova, Olga Dolnik, Philip Lawrence, Viktor E Volchkov
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science (PLoS) 2014-11-01
סדרה:PLoS Pathogens
גישה מקוונת:http://europepmc.org/articles/PMC4239094?pdf=render
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