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Non-Metabolic Functions of PKM2 Contribute to Cervical Cancer Cell Proliferation Induced by the HPV16 E7 Oncoprotein

Pyruvate kinase M2 (PKM2) mainly catalyzes glycolysis, but it also exerts non-glycolytic functions in several cancers. While it has been shown to interact with the human papillomavirus 16 (HPV16) E7 oncoprotein, the functional significance of PKM2 in HPV-associated cervical cancer has been elusive....

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Principais autores: Seoung-Ae Lee, Charles Ho, Madison Troxler, Chin-Yo Lin, Sang-Hyuk Chung
פורמט: Artigo
שפה:Inglês
יצא לאור: MDPI AG 2021-03-01
סדרה:Viruses
נושאים:
HPV16 E7
cervical cancer
PKM2
ML265
non-pyruvate kinase function
גישה מקוונת:https://www.mdpi.com/1999-4915/13/3/433
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