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Prescription opioids induced microbial dysbiosis worsens severity of chronic pancreatitis and drives pain hypersensitivity

ABSTRACTOpioids, such as morphine and oxycodone, are widely used for pain management associated with chronic pancreatitis (CP); however, their impact on the progression and pain sensitivity of CP has never been evaluated. This report investigates the impact of opioid use on the severity of CP, pain...

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Principais autores: Kousik Kesh, Junyi Tao, Nillu Ghosh, Richa Jalodia, Salma Singh, Rajinder Dawra, Sabita Roy
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis Group 2024-12-01
coleção:Gut Microbes
Assuntos:
Chronic pancreatitis
gastrointestinal microbiome
opioid
morphine
oxycodone
pain
Acesso em linha:https://www.tandfonline.com/doi/10.1080/19490976.2024.2310291
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