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Central and peripheral analgesic active components of triterpenoid saponins from Stauntonia chinensis and their action mechanism

Triterpenoid saponins from Stauntonia chinensis have been proven to be a potential candidate for inflammatory pain relief. Our pharmacological studies confirmed that the analgesic role of triterpenoid saponins from S. chinensis occurred via a particular increase in the inhibitory synaptic response i...

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Principais autores: Ji-Hong Gong, Chang-Ming Zhang, Bo Wu, Zi-Xun Zhang, Zhong-Yan Zhou, Jia-Hui Zhu, Han Liu, Yi Rong, Qian Yin, Ya-Ting Chen, Rong Zheng, Guang-Zhong Yang, Xiao-Fei Yang, Su Chen
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2023-10-01
Serier:Frontiers in Pharmacology
Fag:
stauntonia chinensis
triterpenoid saponins
analgesia
neural signal transduction
transient receptor potential vanilloid 1
Online adgang:https://www.frontiersin.org/articles/10.3389/fphar.2023.1275041/full
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