The goya mouse mutant reveals distinct newly identified roles for MAP3K1 in the development and survival of cochlear sensory hair cells

Mitogen-activated protein kinase, MAP3K1, plays an important role in a number of cellular processes, including epithelial migration during eye organogenesis. In addition, studies in keratinocytes indicate that MAP3K1 signalling through JNK is important for actin stress fibre formation and cell migra...

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Principais autores:	Andrew Parker, Sally H. Cross, Ian J. Jackson, Rachel Hardisty-Hughes, Susan Morse, George Nicholson, Emma Coghill, Michael R. Bowl, Steve D. M. Brown
Formato:	Artigo
Idioma:	Inglês
Publicado em:	The Company of Biologists 2015-12-01
coleção:	Disease Models & Mechanisms
Assuntos:	MAP3K1 Supernumerary outer hair cells Cochlear development Sensory hair cell survival Hearing loss
Acesso em linha:	http://dmm.biologists.org/content/8/12/1555
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