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Gualou Guizhi Granule inhibits microglia-mediated neuroinflammation to protect against neuronal apoptosis in vitro and in vivo

ObjectNeuroinflammation mediated by microglia has emerged as a critical factor in ischemic stroke and neuronal damage. Gualou Guizhi Granule (GLGZG) has been shown to suppress inflammation in lipopolysaccharide (LPS)-activated microglia, though the underlying mechanisms and its protective effects...

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Principais autores: Xuezhen Li, Han Huang, Yanan Li, Yi Feng, Jinxuan Wang, Shuping Luo, Yaping Chen, Yuqin Zhang, Guohong Yan, Lihong Nan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2025-01-01
coleção:Frontiers in Immunology
Assuntos:
ischemic stroke
Gualou Guizhi Granule
Notch
microglia
neuroinflammation
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1527986/full
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