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Structure elements can be predicted using the contact volume among protein residues

Previously, the structure elements of dihydrofolate reductase (DHFR) were determined using comprehen­sive Ala-insertion mutation analysis, which is assumed to be a kind of protein “building blocks.” It is hypo­thesized that our comprehension of the structure elements could lead to understanding how...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Yasumichi Takase, Yoichi Yamazaki, Yugo Hayashi, Sachiko Toma-Fukai, Hironari Kamikubo
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society of Japan 2021-03-01
Schriftenreihe:Biophysics and Physicobiology
Schlagworte:
contact map
folding element
residue–residue contact
precipitate ratio profile
protein folding
Online-Zugang:https://doi.org/10.2142/biophysico.bppb-v18.006
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