Sec61β maintains cytoplasmic proteostasis via ARIH1-mediated translational repression upon ER stress

Abstract Disrupted proteostasis causes various degenerative diseases, and organelle homeostasis is therefore maintained by elaborate mechanisms. Endoplasmic reticulum (ER) stress-induced preemptive quality control (ERpQC) counteracts stress by reducing ER load through inhibiting the translocation of...

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主要な著者:	Hisae Kadowaki, Tomohisa Hatta, Kazuma Sugiyama, Tomohiro Fukaya, Takao Fujisawa, Takashi Hamano, Naoya Murao, Yasunari Takami, Shuya Mitoma, Tohru Natsume, Katsuaki Sato, Hiromi Hirata, Tamayo Uechi, Hideki Nishitoh
フォーマット:	Artigo
言語:	Inglês
出版事項:	Springer Nature 2026-01-01
シリーズ:	EMBO Reports
主題:	ERpQC ER Stress Proteostasis Translational Regulation
オンライン･アクセス:	https://doi.org/10.1038/s44319-026-00690-y
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