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Anisotropic ESCRT-III architecture governs helical membrane tube formation

ESCRT-III proteins assemble into ubiquitous membrane-remodeling polymers during many cellular processes. Here, the authors use cryo-ET, cryo-EM and mathematical modeling to reveal how the shape of the helical membrane tube arises from the assembly of two distinct bundles of helical filaments.

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Detalles Bibliográficos
Principais autores: Joachim Moser von Filseck, Luca Barberi, Nathaniel Talledge, Isabel E. Johnson, Adam Frost, Martin Lenz, Aurélien Roux
Formato: Artigo
Idioma:Inglês
Publicado: Nature Portfolio 2020-05-01
Series:Nature Communications
Acceso en liña:https://doi.org/10.1038/s41467-020-15327-4
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