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Clinical and genetic characteristics of BAP1-mutated non-uveal and uveal melanoma

BackgroundScreening for gene mutations has become routine clinical practice across numerous tumor entities, including melanoma. BAP1 gene mutations have been identified in various tumor types and acknowledged as a critical event in metastatic uveal melanoma, but their role in non-uveal melanoma rema...

Ful tanımlama

Kaydedildi:
Asıl Yazarlar: Johanna Matull, Jan-Malte Placke, Georg Lodde, Anne Zaremba, Jochen Utikal, Patrick Terheyden, Claudia Pföhler, Rudolf Herbst, Alexander Kreuter, Julia Welzel, Julia Kretz, Inga Möller, Antje Sucker, Annette Paschen, Elisabeth Livingstone, Lisa Zimmer, Eva Hadaschik, Selma Ugurel, Dirk Schadendorf, Carl Maximilian Thielmann, Klaus Georg Griewank
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2024-06-01
Seri Bilgileri:Frontiers in Immunology
Konular:
BAP1
non-uveal melanoma
uveal melanoma
mutation profiling
immunotherapy
Online Erişim:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1383125/full
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