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Chicken DDX3X Activates IFN-β via the chSTING-chIRF7-IFN-β Signaling Axis

Asp-Glu-Ala-Asp (DEAD)-box polypeptide 3 X-linked (DDX3X) is an ATP-dependent RNA helicase, In addition to involvement of eukaryotic gene expression regulation, mammalian DDX3X has recently been found to regulate IFN-β production via the adaptor MAVS mediated cascade signaling. In our studies, we de...

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Bibliografische gegevens
Hoofdauteurs: Qiaona Niu, Yuqiang Cheng, Hengan Wang, Yaxian Yan, Jianhe Sun
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2019-04-01
Reeks:Frontiers in Immunology
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Online toegang:https://www.frontiersin.org/article/10.3389/fimmu.2019.00822/full
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