Genomic analyses of high‐grade neuroendocrine gynecological malignancies reveal a unique mutational landscape and therapeutic vulnerabilities

High‐grade neuroendocrine carcinoma of gynecologic origin (NEC‐GYN) is a highly aggressive cancer that often affects young women. The clinical management of NEC‐GYN is typically extrapolated from its counterpart, small cell carcinoma of the lung (SCLC), but, unfortunately, available therapies have l...

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Autores principales:	Haider Mahdi, Amy Joehlin‐Price, Esther Elishaev, Afshin Dowlati, Ata Abbas
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Wiley 2021-12-01
Colección:	Molecular Oncology
Materias:	CDK4/6 inhibitors gynecologic neuroendocrine carcinoma immunotherapy targets PARP inhibitors RB1 YAP1
Acceso en línea:	https://doi.org/10.1002/1878-0261.13057
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!