A Glyoxalase-1 Knockdown Does Not Have Major Short Term Effects on Energy Expenditure and Atherosclerosis in Mice

Objective. Glyoxalase-1 is an enzyme detoxifying methylglyoxal (MG). MG is a potent precursor of advanced glycation endproducts which are regarded to be a key player in micro- and macrovascular damage. Yet, the role of Glo1 in atherosclerosis remains unclear. In this study, the effect of Glo1 on mou...

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Detalhes bibliográficos

Principais autores:	Markus Wortmann, Maani Hakimi, Thomas Fleming, Andreas S. Peters, Tjeerd P. Sijmonsma, Stephan Herzig, Peter P. Nawroth, Dittmar Böckler, Susanne Dihlmann
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2016-01-01
Colecção:	Journal of Diabetes Research
Acesso em linha:	http://dx.doi.org/10.1155/2016/2981639
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