Comparison of rituximab induction and maintenance regimens in anti-neutrophil cytoplasmic antibodies (ANCA)-associated vasculitis: PK/PD modelling of ANCA and gammaglobulin levels in real-world patientsResearch in context

Summary: Background: We aimed to provide pharmacokinetic-pharmacodynamic (PK/PD) rationale for selecting the optimal induction and maintenance dosing regimens in ANCA-associated vasculitis (AAV) using a population modelling approach based on PK, ANCA, and gammaglobulins data from a real-world cohor...

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מידע ביבליוגרפי

Principais autores:	Blaise Pasquiers, Benoit Blanchet, Xavier Puéchal, Xavier Declèves, Pascal Cohen, Claire Goulvestre, Marion Casadevall, Inès Benhabiles, Michel Vidal, David Ternant, Benjamin Terrier, Alicja Puszkiel
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Elsevier 2025-11-01
סדרה:	EBioMedicine
נושאים:	Rituximab Anti-neutrophil cytoplasmic antibodies Gammaglobulins Population pharmacokinetics PK/PD Anti-neutrophil cytoplasmic antibodies-associated vasculitis
גישה מקוונת:	http://www.sciencedirect.com/science/article/pii/S2352396425004335
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