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Environmental regulation of toxin production in Bacillus anthracis.

Pathogenic Bacillus anthracis strains carry two plasmids - pX01, which encodes a tripartite protein exotoxin complex (PA, LF, and EF); and pX02, which encodes a poly-D-gamma-glutamic acid capsule. A multidomain transcription factor, AtxA, regulates the expression of these virulence genes. AtxA has t...

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Bibliografische Detailangaben
Hauptverfasser: Ankur Bothra, Andrei Pomerantsev, Benjamin Schwarz, Anupam Mondal, Eric Bohrnsen, Nitika Sangwan, Kaitlin A Stromberg, Mahtab Moayeri, Qian Ma, Rasem Fattah, Sundar Ganesan, Catharine M Bosio, Stephen H Leppla
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2025-12-01
Schriftenreihe:PLoS Pathogens
Online-Zugang:https://doi.org/10.1371/journal.ppat.1013587
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