Transmigration of Neutrophils From Patients With Familial Mediterranean Fever Causes Increased Cell Activation

Familial Mediterranean fever (FMF) is caused by pyrin-encoding MEFV gene mutations and characterized by the self-limiting periods of intense inflammation, which are mainly mediated by a massive influx of polymorphonuclear neutrophils (PMNs) into the inflamed sites. Perturbation of actin polymerizati...

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Detalhes bibliográficos

Principais autores:	Anush Martirosyan, David Poghosyan, Susanna Ghonyan, Nune Mkrtchyan, Gayane Amaryan, Gayane Manukyan
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2021-05-01
coleção:	Frontiers in Immunology
Assuntos:	Familial Mediterranean fever neutrophils fresh/aged neutrophils transmigration IL-1β immunophenotype
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.672728/full
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