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In Search of a Feedback Signal for Closed-Loop Deep Brain Stimulation: Stimulation of the Subthalamic Nucleus Reveals Altered Glutamate Dynamics in the Globus Pallidus in Anesthetized, 6-Hydroxydopamine-Treated Rats

Deep Brain Stimulation (DBS) of the subthalamic nucleus (STN) is a surgical procedure for alleviating motor symptoms of Parkinson’s Disease (PD). The pattern of DBS (e.g., the electrode pairs used and the intensity of stimulation) is usually optimized by trial and error based on a subjective evaluat...

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Principais autores: Mykyta M. Chernov, Christina B. Swan, James C. Leiter
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2023-04-01
Serier:Biosensors
Fag:
deep brain stimulation
subthalamic nucleus
globus pallidus
pseudorandom binary sequence
glutamate biosensor
Parkinson’s disease
Online adgang:https://www.mdpi.com/2079-6374/13/4/480
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