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The Membrane-Bound Notch Regulator Mnr Supports Notch Cleavage and Signaling Activity in <i>Drosophila melanogaster</i>

The Notch signaling pathway is pivotal to cellular differentiation. Activation of this pathway involves proteolysis of the Notch receptor and the release of the biologically active Notch intracellular domain, acting as a transcriptional co-activator of Notch target genes. While the regulation of Not...

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Autori principali: Anja C. Nagel, Dominik Müller, Mirjam Zimmermann, Anette Preiss
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2021-11-01
Serie:Biomolecules
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Accesso online:https://www.mdpi.com/2218-273X/11/11/1672
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