Diagnostic yield of genetic testing in a multinational heterogeneous cohort of 2088 DCM patients

BackgroundFamilial dilated cardiomyopathy (DCM) causes heart failure and may lead to heart transplantation. DCM is typically a monogenic disorder with autosomal dominant inheritance. Currently disease-causing variants have been reported in over 60 genes that encode proteins in sarcomeres, nuclear la...

Fuld beskrivelse

Bibliografiske detaljer

Principais autores:	Krista Heliö, Marcos Cicerchia, Julie Hathaway, Johanna Tommiska, Johanna Huusko, Inka Saarinen, Lotta Koskinen, Mikko Muona, Ville Kytölä, Janica Djupsjöbacka, Massimiliano Gentile, Pertteli Salmenperä, Tero-Pekka Alastalo, Christian Steinberg, Tiina Heliö, Jussi Paananen, Samuel Myllykangas, Juha Koskenvuo
Format:	Artigo
Sprog:	Inglês
Udgivet:	Frontiers Media S.A. 2023-09-01
Serier:	Frontiers in Cardiovascular Medicine
Fag:	dilated cardiomyopathy cardiomyopathy genetic testing next generation sequencing diagnostic yield
Online adgang:	https://www.frontiersin.org/articles/10.3389/fcvm.2023.1254272/full
Tags:	Tilføj Tag Ingen Tags, Vær først til at tagge denne postø!