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Autoantibodies to the TSH Receptor—from discovery to understanding the mechanisms of action and to new therapeutics

Prior to 1956, Graves’ hyperthyroidism was thought to be due to high levels of TSH but in that year Adams & Purves demonstrated the presence of a thyroid stimulator in Graves’ sera with a prolonged time course of action (long-acting thyroid stimulator, LATS) quite distinct from TSH. LATS was onl...

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Bibliografiska uppgifter
Huvudupphov: Bernard Rees Smith
Materialtyp: Artigo
Språk:Inglês
Utgiven: The Japan Endocrine Society 2025-11-01
Serie:Endocrine Journal
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Länkar:https://www.jstage.jst.go.jp/article/endocrj/72/11/72_EJ25-0127/_html/-char/en
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