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An integrative analysis of DNA methylation and gene expression to predict lung adenocarcinoma prognosis

Background: Abnormal DNA methylation of gene promoters is an important feature in lung adenocarcinoma (LUAD). However, the prognostic value of DNA methylation remains to be further explored. Objectives. We sought to explore DNA methylation characteristics and develop a quantifiable criterion related...

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Principais autores: Liexi Xu, Zhengrong Huang, Zihang Zeng, Jiali Li, Hongxin Xie, Conghua Xie
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2022-08-01
Serier:Frontiers in Genetics
Fag:
DNA methylation
integrative analysis
lung adenocarcinoma
prognosis
TCGA
Online adgang:https://www.frontiersin.org/articles/10.3389/fgene.2022.970507/full
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