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Butyrolactone-I from Coral-Derived Fungus Aspergillus terreus Attenuates Neuro-Inflammatory Response via Suppression of NF-κB Pathway in BV-2 Cells

Butyrolactone-I (ZB5-1) from the coral-derived fungus Aspergillus terreus was investigated in this study to estimate its anti-neuroinflammatory effects on lipopolysaccharide (LPS)-induced BV-2 microglia cells. MTT assay indicated that ZB5-1 in tested concentrations had no cytotoxicity on BV-2 cells,...

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Principais autores: Yuan Yuan Zhang, Yi Zhang, Yuan-Bei Yao, Xiao-Ling Lei, Zhong-Ji Qian
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2018-06-01
Series:Marine Drugs
Assuntos:
butyrolactone-I
Aspergillus terreus
microglia
neuro-inflammation
Acceso en liña:http://www.mdpi.com/1660-3397/16/6/202
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