Comparative Forced Degradation Study of Anticomplement C5 Biosimilar and Originator Monoclonal Antibodies

<b>Background/Objectives</b>: The stress testing of biotherapeutic products is a critical component of drug development, enabling the assessment of stability, biosimilarity, and degradation pathways. Subjecting biosimilar monoclonal antibodies to controlled stress conditions yields essential insight...

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Bibliografische Detailangaben

Hauptverfasser:	Merve Celik Yamaci, Ceren Pamukcu, Yigit Erdemgil, Ahmet Emin Atik, Zeynep Zulfiye Yildirim Keles, Ozge Can
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2025-04-01
Schriftenreihe:	Pharmaceuticals
Schlagworte:	monoclonal antibody biosimilar mAb forced degradation size exclusion chromatography isoelectric focusing capillary electrophoresis
Online-Zugang:	https://www.mdpi.com/1424-8247/18/4/579
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