Loss of Early Growth Response Protein 1 in the Liver Leads to Hepatic Lipid Accumulation Driven by an Imbalance Between Fatty Acid β-Oxidation and Oxidative Phosphorylation

Background and Aims: Metabolic-associated fatty liver disease is a worldwide health problem characterized by increased hepatic lipid accumulation, leading to conditions like steatohepatitis, cirrhosis, and liver cancer. Early growth response protein 1 (EGR1) gene encodes an immediate early transcrip...

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Autors principals:	Cristy R.C. Verzijl, Dicky Struik, Albert Gerding, Roos E. Eilers, Rachel E. Thomas, Mirjam Koster, Miriam Langelaar-Makkinje, Marieke Smit, Nicolette Huijkman, Rick Havinga, Niels Kloosterhuis, Vincent W. Bloks, Justina C. Wolters, Jan Freark de Boer, Bart van de Sluis, Barbara M. Bakker, Johan W. Jonker
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2026-01-01
Col·lecció:	Gastro Hep Advances
Matèries:	Metabolic-Associated Fatty Liver Disease Early Growth Response Protein 1 Mitochondrial Function Fatty Acid Oxidation
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S2772572326000026
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