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Case Report: Malignant peritoneal mesothelioma with TFG-ROS1 fusion responds to crizotinib

BackgroundMalignant peritoneal mesothelioma (MPM) is an exceptionally rare tumor type, and its molecular properties are poorly understood. In recent years, gene rearrangement has been found in a subset of MPMs. However, ROS1 rearrangement has not been previously reported in MPM.Case presentationHere...

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Principais autores: Wei Ye, Peng Li, Cong Fu, Tong Zhou
פורמט: Artigo
שפה:Inglês
יצא לאור: Frontiers Media S.A. 2025-10-01
סדרה:Frontiers in Oncology
נושאים:
malignant peritoneal mesothelioma
TFG-ROS1 rearrangement
ROS1 p.K1991N
crizotinib
resistance
case report
גישה מקוונת:https://www.frontiersin.org/articles/10.3389/fonc.2025.1617457/full
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