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Rapamycin Attenuates Aldosterone-Induced Tubulointerstitial Inflammation and Fibrosis

Background/Aim: Aldosterone (Aldo), a mediator of kidney fibrosis, is implicated in the pathogenesis of chronic kidney diseases (CKD). The aim of this study was to evaluate the regulatory role of rapamycin (Rap) in Aldo-induced tubulointerstitial inflammation and fibrosis. Methods: Uninephrectomized...

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Principais autores: Bin Wang, Wei Ding, Minmin Zhang, Hongmei Li, Yong Gu
Format: Artigo
Sprog:Inglês
Udgivet: Cell Physiol Biochem Press GmbH & Co KG 2015-01-01
Serier:Cellular Physiology and Biochemistry
Fag:
Tubulointerstitial Inflammation
Rapamycin
Aldosterone
Fibrosis
Online adgang:http://www.karger.com/Article/FullText/369680
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