Identification and editing of stem-like cells in methylcholanthrene-induced sarcomas

The cancer stem cell (CSC) paradigm posits that specific cells within a tumor, so-called CSC-like cells, have differing levels of tumorigenicity and chemoresistance. Original studies of CSCs identified them in human cancers and utilized mouse xenograft models to define the cancer initiating properti...

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Principais autores:	Emilie T. E. Gross, Carlos D. Peinado, Yujin Jung, Semi Han, Beichen Liu, Endi K. Santosa, Jack D. Bui
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis Group 2019-01-01
coleção:	OncoImmunology
Assuntos:	cancer stem cells cancer immune surveillance cancer immunoediting immune therapy mca sarcoma
Acesso em linha:	http://dx.doi.org/10.1080/2162402X.2017.1404212
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