Iron content of glioblastoma tumours and role of ferrous iron in the hypoxic response in vitro

IntroductionGlioblastomas are an aggressive primary brain cancer, characterised by hypoxia and poor patient survival. Iron is the most abundant transition metal in the brain, yet data on the iron content of brain cancers is sparse. Ferrous iron is an essential cofactor for a super-family of enzymes,...

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Hlavní autoři:	Citra Praditi, Eira Beverley-Stone, Malcolm Reid, Eleanor R. Burgess, Rebekah L. Crake, Margreet C.M. Vissers, Janice A. Royds, Tania L. Slatter, Gabi U. Dachs, Elisabeth Phillips
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2025-03-01
Edice:	Frontiers in Oncology
Témata:	brain cancer survival elemental iron ferrous iron hypoxia glioblastoma
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fonc.2025.1536549/full
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