Strain-specific differences in the response to egg-derived versus recombinant protein influenza vaccines

ABSTRACT The 2023/2024 influenza vaccine included an updated H1N1 component designed to better match a new clade of H1N1 that had multiple mutations in antigenic epitopes of hemagglutinin. Despite this update, the vaccine trended toward being less effective against the vaccine-matched H1N1 clade tha...

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Detalhes bibliográficos

Principais autores:	Andrea N. Loes, Rosario Araceli L. Tarabi, Shuk Hang Li, Reilly K. Atkinson, John Huddleston, Caroline Kikawa, Tachianna Griffiths, Elizabeth M. Drapeau, Sook-San Wong, Samuel M. S. Cheng, Nancy H. L. Leung, Sarah Cobey, Benjamin J. Cowling, Trevor Bedford, Scott E. Hensley, Jesse D. Bloom
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology 2026-06-01
coleção:	Journal of Virology
Assuntos:	influenza vaccine hemagglutinin egg adaptation sequencing-based neutralization assay pdmH1N1 influenza
Acesso em linha:	https://journals.asm.org/doi/10.1128/jvi.00317-26
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