Protection Against Dopaminergic Neurodegeneration in Parkinson’s Disease–Model Animals by a Modulator of the Oxidized Form of DJ-1, a Wild-type of Familial Parkinson’s Disease–Linked PARK7

Abstract.: DJ-1, Parkinson’s disease PARK7, acts as an oxidative stress sensor in neural cells. Recently, we identified the DJ-1 modulator UCP0054278 by in silico virtual screening. However, the effect of the peripheral administration of UCP0054278 on an in vivo Parkinson’s disease (PD) model is unc...

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Bibliografische Detailangaben

Hauptverfasser:	Masatoshi Inden, Yoshihisa Kitamura, Kazunori Takahashi, Kazuyuki Takata, Natsuko Ito, Rina Niwa, Risa Funayama, Kaneyasu Nishimura, Takashi Taniguchi, Toshio Honda, Takahiro Taira, Hiroyoshi Ariga
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2011-01-01
Schriftenreihe:	Journal of Pharmacological Sciences
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S1347861319306292
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