Regulation of the tyrosine phosphorylation of Phospholipid Scramblase 1 in mast cells that are stimulated through the high-affinity IgE receptor.

Engagement of high-affinity immunoglobulin E receptors (FcεRI) activates two signaling pathways in mast cells. The Lyn pathway leads to recruitment of Syk and to calcium mobilization whereas the Fyn pathway leads to phosphatidylinositol 3-kinase recruitment. Mapping the connections between both path...

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Autori principali:	Asma Kassas, Ivan C Moura, Yumi Yamashita, Jorg Scheffel, Claudine Guérin-Marchand, Ulrich Blank, Peter J Sims, Therese Wiedmer, Renato C Monteiro, Juan Rivera, Nicolas Charles, Marc Benhamou
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Public Library of Science (PLoS) 2014-01-01
Serie:	PLoS ONE
Accesso online:	http://europepmc.org/articles/PMC4188579?pdf=render
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