Germline burden of rare damaging variants negatively affects human healthspan and lifespan
Heritability of human lifespan is 23–33% as evident from twin studies. Genome-wide association studies explored this question by linking particular alleles to lifespan traits. However, genetic variants identified so far can explain only a small fraction of lifespan heritability in humans. Here, we r...
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| Principais autores: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications Ltd
2020-04-01
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| coleção: | eLife |
| Assuntos: | |
| Acesso em linha: | https://elifesciences.org/articles/53449 |
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