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Spatially organized macrophage–T-cell crosstalk in cervical cancer: insights from single-cell and spatial omics

Immunotherapy has transformed the therapeutic landscape of advanced cervical cancer, yet clinical benefit remains limited by a highly heterogeneous and immunosuppressive tumor microenvironment. Traditional paradigms, including binary M1/M2 macrophage polarization and models that interpret T-cell dys...

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Autors principals: Li Huang, Nan Lin, Hao Li, Yong Hu
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2026-07-01
Col·lecció:Frontiers in Immunology
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Accés en línia:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1896004/full
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