MEK-inhibitors decrease Nfix in muscular dystrophy but induce unexpected calcifications, partially rescued with Cyanidin diet

Summary: Muscular dystrophies (MDs) are incurable genetic myopathies characterized by progressive degeneration of skeletal muscles. Dystrophic mice lacking the transcription factor Nfix display morphological and functional improvements of the disease. Recently, we demonstrated that MAPK signaling pa...

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Bibliografski detalji

Glavni autori:	Giuseppe Angelini, Emanuele Capra, Francesca Rossi, Giada Mura, Marielle Saclier, Valentina Taglietti, Gabriele Rovetta, Raffaele Epis, Giorgia Careccia, Chiara Bonfanti, Graziella Messina
Format:	Artigo
Jezik:	Inglês
Izdano:	Elsevier 2024-01-01
Serija:	iScience
Teme:	Pathophysiology Drugs Cancer
Online pristup:	http://www.sciencedirect.com/science/article/pii/S2589004223027736
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