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Uncovering the electrical synapse proteome in retinal neurons via in vivo proximity labeling

Electrical synapses containing Connexin 36 (Cx36) represent the main means for direct electrical communication among neurons in the mammalian nervous system. However, little is known about the protein complexes that constitute these synapses. In the present study, we applied different BioID strategi...

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Principais autores: Stephan Tetenborg, Eyad Shihabeddin, Elizebeth Olive Akansha Manoj Kumar, Crystal L Sigulinsky, Karin Dedek, Ya-Ping Lin, Fabio A Echeverry, Hannah Hoff, Alberto E Pereda, Bryan W Jones, Christophe P Ribelayga, Klaus Ebnet, Ken Matsuura, John O'Brien
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications Ltd 2026-05-01
coleção:eLife
Assuntos:
electrical synapse
turboID
connexin 36
AII amacrine cells
synaptic scaffolds
AAV
Acesso em linha:https://elifesciences.org/articles/105935
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