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Targeting Enterococcus faecalis HMG-CoA reductase with a non-statin inhibitor

High-throughput in vitro screening and crystal structures identify a non-statin inhibitor of HMG-CoA reductase for novel antibacterial drug design.

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Bibliografski detalji
Glavni autori: Sucharita Bose, C. Nicklaus Steussy, Daneli López-Pérez, Tim Schmidt, Samadhi C. Kulathunga, Mohamed N. Seleem, Mark Lipton, Andrew D. Mesecar, Victor W. Rodwell, Cynthia V. Stauffacher
Format: Artigo
Jezik:Inglês
Izdano: Nature Portfolio 2023-04-01
Serija:Communications Biology
Online pristup:https://doi.org/10.1038/s42003-023-04639-y
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