The effects of ARID1A mutations on colorectal cancer and associations with PD‐L1 expression by stromal cells

Abstract Background ARID1A is a component of the SWI/SNF complex, which controls the accessibility of proteins to DNA. ARID1A mutations are frequently observed in colorectal cancers (CRCs) and have been reported to be associated with high mutational burden and tumor PD‐L1 expression in vitro. Aim To...

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Hlavní autoři:	Tomohiro Kamori, Eiji Oki, Yoshifumi Shimada, Qingjiang Hu, Yuichi Hisamatsu, Koji Ando, Mototsugu Shimokawa, Toshifumi Wakai, Yoshinao Oda, Masaki Mori
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Wiley 2022-01-01
Edice:	Cancer Reports
Témata:	ARID1A colorectal cancer microsatellite instability PD‐L1
On-line přístup:	https://doi.org/10.1002/cnr2.1420
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